Endocrine Abstracts

Background: Obesity exacerbates many aspects of the PCOS phenotype, especially cardiovascular risk factors, infertility. The objective of the study was to determine the effects of overweight and obesity on the metabolic features of PCOS.Material and methods: 116 PCOS women (according to Rotterdam criteria, mean age 27.16±3.87 years) were investigated in Vilnius city (Lithuania) in 2009–2011. Height, body mass and waist circumference were measur...

Background: The objective of the study was to compare distributions of subcutaneous adipose tissue and metabolic parameters in lean women with PCOS and lean healthy women.Materials and methods: PCOS women (according to Rotterdam criteria, mean age 26.54±3.65 years) and 70 healthy control women (mean age 27.84±3.63 years) were investigated in Vilnius city (Lithuania) in 2009–2011. A skinfold caliper device was used to measure skinfolds thic...

The incidence of thyroid cancer (TC) is increasing over time. Follow up and adequate treatment of patients with TC is important in everyday routine practice. The aim of the study was to evaluate peculiarities of clinical and pathologic characteristics of patients with TC, and their management after surgery.Material and methods: We conducted retrospective review of medical records of 116 patients with TC after thyroid surgery followed up in Vilnius Antaka...

The objective was to assess rate of impaired glucose regulation and progression to diabetes in adults using routinely collected health-care data.Material and methods: We conducted an audit on results of 75-g standardized oral glucose tolerance tests (OGTT) performed at Vilnius Antakalnio Outpatient Clinic from 3rd Jan 2011 to 15th Dec 2014 and analysed data of adult patients. We excluded from analysis results of 358 patients who didn’t perform 2-h p...

Mood disturbances accompanying the symptoms and hormonal abnormalities are important, but underestimated, in polycystic ovary syndrome (PCOS). Our objective was to assess psychological features in women with and without PCOS.Materials and methods: We investigated 116 PCOS women (according to the Rotterdam criteria) and 81 healthy control women in Vilnius city (Lithuania) in 2009–2011. Levels of anxiety and depression were measured using the Hospital...

: Two-way interactions between thyroid and kidney functions are known. Chronic kidney disease (CKD) is accompanied by changes in synthesis, secretion, metabolism, and elimination of thyroid hormones, increased risk of hypothyroidism, rarely subclinical hyperthyroidism, whereas thyroid dysfunction affects physiology of the kidney, renal blood flow, glomerular filtration rate (GFR), tubular function, metabolism of water and electrolytes, and kidney structure. The aim of the stud...

Oral glucose tolerance test (OGTT) is the main tool in population based screening for type 2 diabetes mellitus. Sometimes OGTT results are showing asymptomatic lowering of post-load blood glucose. Post-load plasma glucose (2hPG) level 3.9 mmol/l (70 mg/dl) and lower shows biochemical hypoglycaemia. Biochemical hypoglycaemia might be observed among individuals with abnormal glucose tolerance and in healthy population. The objective of the investigation was to assess a prevalenc...

The objective of the study was to investigate association between BMI, waist circumference, and measures of thyroid function among euthyroid adult women.Material and methods: We analysed retrospective data of 119 euthyroid women participating in Lithuanian screening and prevention program for patients with high cardiovascular risk at Vilnius Antakalnio Outpatient Clinic from Jul 2013 to Dec 2013. Glucose, lipid profile, TSH, and fT4 tests and ...

Background: There are evidences that young adults are at risk for poor vitamin D nutritional status. The objective of this study was to investigate the level of vitamin D in school graduates females and the factors associated with vitamin D status.Material and methods: School graduates females from three Lithuanian cities were enrolled into the project from March to June of 2012. General health, nutrition, physical activity status was assessed by questio...

Hyperglycaemia is one of the most common medical conditions women encounter during pregnancy. The occurrence of gestational diabetes mellitus (GDM) is rising and it represents an important modifiable risk factor for adverse pregnancy outcomes. Similar to GDM, excessive weight gain is associated with a number of undesirable consequences for both the mother and neonate. The aim of this study was to evaluate prevalence of GDM in outpatient practice and investigate associations be...